%0 Journal Article
%T Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation
%J -
%D 2019
%R https://doi.org/10.1016/j.ccell.2018.12.012
%X £¿ WTp53-PUMA pathway drives cancer metabolic switch £¿ PUMA suppresses mitochondrial pyruvate uptake by inactivating MPC £¿ IKK¦Â-mediated phosphorylation of PUMA is important for PUMA-MPC interaction £¿ High levels of PUMA in HCC are correlated with poor prognosis of HCC patient
%U https://www.cell.com/cancer-cell/fulltext/S1535-6108(18)30584-1