%0 Journal Article
%T High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2019.03.045
%X £¿ A leukemia platform allows for saturated shRNA-based synthetic lethality screens £¿ High-complexity shRNA libraries enable lethality identification with high fidelity £¿ Small molecule inhibitors and cancer cell lines confirm predicted lethality £¿ PI3K inhibitors and vincristine synergize in in vivo preclinical mouse trial
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30361-4