%0 Journal Article %T CRISPR-Mediated Editing of the B Cell Receptor in Primary Human B Cells %J - %D 2019 %R https://doi.org/10.1016/j.isci.2019.01.032 %X £¿ Methods to perform Cas9-mediated gene editing in primary human B cells are reported £¿ Homologous recombination was confirmed by sequencing, PCR, and restriction digest £¿ Replacement of B cell receptor loci in primary human B cells was achieved £¿ Reprogramming the antibody specificity of B cells could have clinical importanc %U https://www.cell.com/iscience/fulltext/S2589-0042(19)30034-3