%0 Journal Article
%T Epithelial-Mesenchymal Transition Directs Stem Cell Polarity via Regulation of Mitofusin
%J -
%D 2019
%R https://doi.org/10.1016/j.cmet.2018.11.004
%X £¿ EMT induces mitochondrial fusion through upregulation of MFN1 £¿ MFN1 is required for PKC¦Æ-mediated NUMB phosphorylation for asymmetric cell division £¿ MFN1-PKC¦Æ tethers fused mitochondria for segregation into stem cell progeny £¿ Mitochondrial fusion enhances GSH synthesis to promote stem cell self-renewa
%U https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30681-8