%0 Journal Article
%T Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
%J -
%D 2019
%R https://doi.org/10.1016/j.cmet.2018.10.005
%X £¿ AMPK does not phenocopy the lung tumor-suppressor role of its activator LKB1 £¿ AMPK deletion reduces tumor burden in KrasG12D and Kras p53 £¿/£¿ lung cancer models £¿ AMPK is required during glucose deprivation to induce Tfeb and Tfe3 activation £¿ Tfe3 activity is required for growth of mouse lung tumor
%U https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30637-5