%0 Journal Article
%T Dismantling a Toxin to Disarm a Superbug
%J -
%D 2019
%R https://doi.org/10.1016/j.tips.2019.01.007
%X Clostridium difficile (Clostridioides difficile) is a toxin-producing, multidrug-resistant bacterium. Inhibiting the effects of toxins, which are responsible for the symptoms of disease, is viewed as a promising non-antibiotic approach to treat C. difficile infection (CDI). By inducing premature activation of toxins, Ivarsson and colleagues ( Cell Chemical Biology 2018; http://doi.org/10.1016/j.chembiol.2018.10.002) uncover a clever new strategy to block toxin action
%U https://www.cell.com/trends/pharmacological-sciences/fulltext/S0165-6147(19)30018-5