%0 Journal Article
%T Resident Macrophage Lookalikes of Unexpected Origin
%J -
%D 2019
%R https://doi.org/10.1016/j.devcel.2019.05.006
%X In this issue of Developmental Cell, Lin et al. (2019) Lin X. Zhou Q. Zhao C. Lin G. Xu J. Wen Z. An ectoderm-derived myeloid-like cell population functions as antigen transporters for Langerhans cells in zebrafish epidermis. Dev. Cell. 2019; 49 ( this issue) : 605-617 Google Scholar identify in zebrafish skin macrophage-like cells that sample the environment through transepithelial protrusions and import antigen from the water for traditional tissue-resident macrophages. Remarkably, these ˇ°metaphocytesˇ± originate from the epidermis, challenging current assumptions about the lineage of tissue-resident macrophages
%U https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30377-6