%0 Journal Article %T Retinoic Acid Induces Hyperactivity, and Blocking Its Receptor Unmasks Light Responses and Augments Vision in Retinal Degeneration %J - %D 2019 %R https://doi.org/10.1016/j.neuron.2019.02.015 %X £¿ Photoreceptor degeneration leads to retinal ganglion cell hyperactivity £¿ Hyperactivity is triggered by overproduction of retinoic acid (RA) £¿ Blocking the RA receptor with drug or gene therapy reduces hyperactivity £¿ RA receptor blockade augments light-evoked behaviors in vision-impaired mic %U https://www.cell.com/neuron/fulltext/S0896-6273(19)30124-2