%0 Journal Article
%T Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity
%J -
%D 2019
%R https://doi.org/10.1016/j.devcel.2019.03.011
%X £¿ SIRT1 expression is frequently decreased in aggressive breast cancers £¿ Reducing SIRT1 levels in breast cancer cells impairs lysosomal acidification £¿ Loss of SIRT1 gives rise to a secretome that promotes cell invasion and survival £¿ SIRT1 mediates these effects by regulating V-ATPase expressio
%U https://www.cell.com/developmental-cell/fulltext/S1534-5807(19)30188-1