%0 Journal Article %T A Major Step towards Defining the Elusive Stumpy Inducing Factor in Trypanosoma brucei %J - %D 2019 %R https://doi.org/10.1016/j.pt.2018.11.009 %X Trypanosoma brucei stumpy forms are the only stage that can transmit from human to tsetse fly. Stumpy formation is regulated by a quorum sensing mechanism that depends on parasite density and an unknown stumpy induction factor (SIF). Recently, an elegant study by Matthews and colleagues (Cell 176, 1¨C12) has identified several crucial components of this pathway, including the putative SIF and its receptor %U https://www.cell.com/trends/parasitology/fulltext/S1471-4922(18)30247-2