%0 Journal Article
%T Mild Cu-Catalyzed Oxidation of Benzylic Boronic Esters to Ketones
%J -
%D 2019
%R https://doi.org/10.1021/acscatal.9b00992
%X The oxidation of benzylic boronic esters directly to the ketone is reported. This mild Cu-catalyzed method uses an ambient atmosphere of air as the terminal oxidant and is notably chemoselective. Oxidation of the C¨CB bond occurs selectively, even in the presence of unprotected alcohols. Initial investigation suggests the reaction proceeds through an alkylboron to Cu transmetalation, peroxide formation, and rearrangement to give the carbonyl
%U https://pubs.acs.org/doi/10.1021/acscatal.9b00992