%0 Journal Article
%T Dual-Action Polymeric Probe: Turn-On Sensing and Removal of Hg2+; Chemosensor for HSO4¨C
%J -
%D 2019
%R https://doi.org/10.1021/acsapm.8b00162
%X A tryptophan-dithiocarbamate-based fluorescent polymeric probe was synthesized, targeting selective recognition and sensing of both cation and anion in aqueous media. Upon treatment with several metal ions, the as-synthesized polymeric probe imparted an irreversible transformation only with Hg2+ ion in aqueous environment with a 5-fold enhancement of the fluorescence (quantum yield (¦µ) = 0.055 ¡ú 0.250) attributed to the photoinduced electron transfer (PET) process. This unique design has an unprecedented detection sensitivity of 300 parts per trillion (ppt) for Hg2+ ions, the most effective water-soluble amino-acid-based polymeric sensor reported so far. Hg2+ ions get trapped when they were passed through a column containing polymeric probe with 94% removal capacity as confirmed by inductively coupled plasma optical emission spectrometer (ICP-OES). Intracellular detection of Hg2+ ions was achieved in human breast cancer cell line, MDA-MB-468, using our synthesized macromolecular probe. In addition, the probe can also be used to detect parts per million (ppm) level of hydrogen sulfate anion (HSO4¨C) in aqueous medium among various anions with high selectivity because of the hydrogen bonding interactions of the polymeric probe with the anion. Although the newly developed tryptophan-based polymeric probe has two distinct binding sites for HSO4¨C and Hg2+, the existence of Hg2+ influences the binding of HSO4¨C
%U https://pubs.acs.org/doi/10.1021/acsapm.8b00162