%0 Journal Article %T Effects of Rapid and Ultra-Rapid Fluid Resuscitation Guided by Blood Lactate Clearance Rate in Diarrheic Calves %A H. ERDOGAN %A H. VOYVODA %J - %D 2019 %R http://dx.doi.org/10.12681/jhvms.20349 http://dx.doi.org/10.12681/jhvms.20349 %X The assessment of the results of intravenous fluid treatment in diarrheal calves is difficult under field conditions. To determine the effects of ultra-rapid (1 h) and rapid (3 h) intravenous infusions with 0.9% NaCl and 1.3% NaHCO3 solutions at a dose of 60 ml/kg on lactate clearance (LC) in calves with diarrhea. Sixty calves, including a healthy control group (n=20) and a group of calves with diarrhea (n=40), were used. Diarrheic calves were divided into two groups (n=20) according to solution type, and each group was then divided into two equal subgroups according to the infusion rate (n=10). Clinical and laboratory inspections of diarrheic calves were performed pre- and post-infusion, and the healthy control group was examined once. LC rates were calculated in the 1 h and 3 h subgroups. Marked improvements in clinical findings related to dehydration were observed in all groups with neonatal diarrhea that were given intravenous infusions with 0.9% NaCl and 1.3% NaHCO3 solutions. End of the infusion, the LC of the 0.9% NaCl and 1.3% NaHCO3 solutions in the ultra-rapid groups was significantly increased by 36.4% and 31.8%, respectively. However, for rapid infusion of the same solutions, 13.6% and 31.8% increases were observed, but the differences were not significant. Under field conditions, the LC of L- and D-lactate varied with the infusion rate, and these variations were significant in ultra-rapid subgroups for both solutions. Further studies will be designed for fluid therapy in calves based on the calculation of LC %K Calf diarrhea %K blood lactate clearance %K rapid infusion %K sodium bicarbonate %K sodium chloride %U https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/20349