%0 Journal Article
%T The effects of transfer day in intracytoplasmic sperm injection (ICSI) pregnancies on first trimester screening test results
%A Tu£¿ba G¨¹rb¨¹z
%J -
%D 2018
%X Objects: To compare first trimesterscrening (FTS) serum markers free ¦Â-human chorionic gonodotropin (free ¦Â-hCG and pregnancy associated plasma protein A (PAPP-A) of blastocyst versus cleavage stage embryo transfers after assisted reproductive technologies (ART). Methods: Retrospective examinations of 123 women who conceived with ART were subjected to FTS from January 2017 to December 2017 at Bah£¿e£¿ehir University G£¿ztepe Medical Park Hospital In Vitro Fertilization (IVF) Unit.The age,gestational week,ultrasound (US) markers and biochemistry markers(PAPP-A,free ¦Â-hCG) were collected.Outcomes were regarded as meaningful when the p < 0.05. Statistical Package For Social Sciences (SPSS) v.17.0 for Windows was preferred to make statistical analysis. Results: PAPP-A amounts were remarkably low in day-3 (cleavage stage embryos) transfer intracytoplasmic sperm injection (ICSI) pregnancies compared to day-5 (blastocyst stage embryos) transfer ICSI pregnancies.Free ¦Â-hCG amounts weren¡¯t significantly different in two groups (p=0.371). NT was unaffected by the transferenceday (p=0.21). Also CRL wasunaffected by the transferenceday (p=0.693). No differences appeared between 3rd and 5th day embryo transference according to maternal age (p=0.616), weight (p=0.693) and gestational age (p=0.742) at sampling. Conclusion: Today, the datas about the effects of ART over the ingredients of combined FTS for chromosomal analysis are contentious yet.Day-3 ICSI pregnancies had meaningfully low PAPP-A amounts which support the requirement to properly set the combined FTS risks algoritm. These outcomes are likely to be because of changings in the placenta of ART pregnancies
%K Assisted reproduction techniques
%K blastocyst
%K cleavage
%K first trimester screening
%U http://dergipark.org.tr/adiyamansaglik/issue/40184/440359