%0 Journal Article
%T EFFECT OF THE INFLAMMATORY BOWEL DISEASES ON CHOROIDAL AND MACULAR THICKNESS
%A Fahrettin AKAY
%J -
%D 2018
%X Abstract Objective: Crohn¡¯s disease (CD) and ulcerative colitis (UC) are a group of inflammatory bowel disease (IBD). Ophthalmic disorders might occur in IBD. The most common findings are episcleritis and uveitis.Then purpose of the study was to evaulate the choroidal and macular thickness (MT and CT) in the IBD and to check it with the disease activity. Methods: IBD group was including 50 patients and the control group consisted of 50 healty volunteers. All participants were tested with spectral domain optical coherence tomography (SD-OCT). The CT values were obtained at seven different points. Results: Mean duration of the IBD was 3.9 ¡À1.5 years. Foveal macular thickness was 258.1 ¡À 14.2 ¦Ìm in study group and 262.7 ¡À 20.9 ¦Ìm in the control group. There was not significant difference between groups(P=0,19). Subfoveal, temporal 500 ¦Ìm, 1000 ¦Ìm, and 1500 ¦Ìm CT measurements were respectively statistically significant in the study group (p<0.001). Mean CT was 289.8 ¡À 25.6 ¦Ìm in study group and 273.9 ¡À 33.2 ¦Ìm in the control group. There was a significant difference between groups (P=0.008). There was no correlation between mean CT and erythrocyte sedimentation rate, C-reactive protein level and other clinical parameters (P£¿ 0,05). Conclusion: Inflammation of the bowels might affect the choroidal vascular structure. £¿NFLAMATUAR BA£¿IRSAK HASTALIKLARININ KORO£¿DAL VE MAKULAR KALINLIK ¨¹ZER£¿NE ETK£¿S£¿ £¿ZET Ama£¿: Crohn hastal£¿£¿£¿ (CD) ve ¨¹lseratif kolit (¨¹K) bir grup inflamatuar barsak hastal£¿£¿£¿d£¿r (IBD) .IBD'de oftalmik bozukluklar ortaya £¿£¿kabilir. En s£¿k g£¿r¨¹len bulgular episklerit ve ¨¹veittir. £¿al£¿£¿man£¿n amac£¿ IBD'deki koroidal ve mak¨¹la kal£¿nl£¿£¿£¿n£¿ (MT ve CT) de£¿erlendirmek ve bunu hastal£¿k aktivitesi ile kontrol etmektir. Y£¿ntem: IBD grubu 50 hastan£¿n 50 sa£¿ g£¿z¨¹n¨¹ i£¿eriyorken, kontrol grubu ise 50 sa£¿l£¿kl£¿ g£¿n¨¹ll¨¹n¨¹n herhangi bir g£¿z¨¹nden olu£¿mu£¿tu. T¨¹m kat£¿l£¿mc£¿lar spectral domain optical coherence tomography (SD-OCT) ile test edildi. CT de£¿erleri yedi farkl£¿ noktada elde edildi. Bulgular: IBD'nin ortalama s¨¹resi 3.9 ¡À 1.5 y£¿l idi. Foveal mak¨¹ler kal£¿nl£¿k; £¿al£¿£¿ma grubunda 258.1 ¡À 14.2 ¦Ìm, kontrol grubunda 262.7 ¡À 20.9 ¦Ìm idi. Gruplar aras£¿nda anlaml£¿ fark yoktu (P = 0,19). Subfoveal, temporal 500 ¦Ìm, 1000 ¦Ìm ve 1500 ¦Ìm CT £¿l£¿¨¹mleri, £¿al£¿£¿ma grubunda s£¿ras£¿yla istatistiksel olarak anlaml£¿yd£¿ (p <0.001). £¿al£¿£¿ma grubunda ortalama BT 289.8 ¡À 25.6 ¦Ìm, kontrol grubunda 273.9 ¡À 33.2 ¦Ìm idi. Gruplar aras£¿nda anlaml£¿ fark vard£¿ (P = 0.008). Ortalama BT ve eritrosit sedimentasyon h£¿z£¿, C-reaktif protein d¨¹zeyi ve di£¿er klinik parametreler aras£¿nda korelasyon yoktu
%K koroidal kal£¿nl£¿k
%K inflamatuar ba£¿£¿rsak hastal£¿klar£¿
%U http://dergipark.org.tr/sdutfd/issue/38995/434235