%0 Journal Article
%T An AAS Dependent Method for Quantitative Analysis of Essential Trace Elements from Blood Samples of Pakistani Female Breast Cancer Patients
%A Ghulam Qadir Chanihoon
%A Ahsanullah Unar
%A Ayaz Ali Memon
%A Tassadaq Hussain Jafar
%A Huma I. Shaikh
%A Ayesha Sani
%A Raj Kumar
%A Sanam Erum Soomro
%A Muqaddas Qureshi
%J Advances in Breast Cancer Research
%P 44-59
%@ 2168-1597
%D 2021
%I Scientific Research Publishing
%R 10.4236/abcr.2021.103004
%X Breast
cancer is the second leading cancer in the world. The long-term exposure of some metallic compounds induces different forms of cancer, including breast
cancer. Trace elements are essential metals for the physiological functions of
the cell on a molecular level and also contribute in treatment of many
diseases. The aim of study was to compare
the level of essential trace elements, sodium, potassium, calcium, iron, and
zinc in breast cancer patients with normal healthy adult women. Total
forty-five patients (age range from 25 - 73 years)
were included in this study and divided into three groups according to three
different stages of breast cancer including tumor-II, tumor-III and tumor-IV. Blood was collected from all
participants after taking history, clinical data and taking consent. However, about fifteen non-cancer healthy women
in age range from 26 - 69 years were subjected to this study. The elemental
concentrations were determined through atomic absorption spectrophotometer subsequent to microwave-induced acid digestion.
The results of Na, K, Zn, Fe, Ca, were observed to decrease in blood samples of breast cancer patients
as compared to non-cancer subjects. The results are reliable with other
numerous literature reported studies, the efficiency, and deficiency of these
trace metals may
%K Breast Cancer Blood Samples
%K Invasive Ductal Carcinoma
%K Tumor Stages
%K Essential Elements
%K FAAS
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=110155