%0 Journal Article
%T An AAS Dependent Method for Quantitative Analysis of Essential Trace Elements from Blood Samples of Pakistani Female Breast Cancer Patients
%A Ghulam Qadir Chanihoon
%A Ahsanullah Unar
%A Ayaz Ali Memon
%A Tassadaq Hussain Jafar
%A Huma I. Shaikh
%A Ayesha Sani
%A Raj Kumar
%A Sanam Erum Soomro
%A Muqaddas Qureshi
%J Advances in Breast Cancer Research
%P 44-59
%@ 2168-1597
%D 2021
%I Scientific Research Publishing
%R 10.4236/abcr.2021.103004
%X Breast
cancer is the second leading cancer in the world. <span style=\"font-family:Verdana;\">The long-term</span><span style=\"font-family:Verdana;\"> exposure </span><span style=\"font-family:Verdana;\">of</span><span style=\"font-family:Verdana;\"> some metallic compounds induces different forms of cancer, including breast
cancer. Trace elements are essential metals for the physiological functions of
the cell on a molecular level and also contribute </span><span style=\"font-family:Verdana;\">in</span> <span style=\"font-family:Verdana;\">treatment</span><span style=\"font-family:Verdana;\"> of many
diseases. </span><span style=\"font-family:Verdana;\">The aim of study was</span><span style=\"font-family:Verdana;\"> to compare
the level of essential trace elements, sodium, potassium, calcium, iron, and
zinc in breast cancer patients with normal healthy adult women. Total
forty-five patients (age range from 25</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:Verdana;\">-</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">73 years)
were included in this study and divided into three groups according to three
different stages of breast cancer including tumor-II, tumor-III </span><span style=\"font-family:Verdana;\">and</span><span style=\"font-family:Verdana;\"> tumor-IV. Blood was collected from all
participants after taking history, clinical data </span><span style=\"font-family:Verdana;\">and</span><span style=\"font-family:Verdana;\"> taking consent. However, about fifteen non-cancer healthy women
in </span><span style=\"font-family:Verdana;\">age</span><span style=\"font-family:Verdana;\"> range from 26</span></span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:Verdana;\">-</span><span style=\"font-family:;\" \"=\"\"> </span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">69 years were subjected to this study. The elemental
concentrations were determined through atomic absorption spectrophotometer </span><span style=\"font-family:Verdana;\">subsequent to</span><span style=\"font-family:Verdana;\"> microwave-induced acid digestion.
The results of Na, K, Zn, Fe, Ca, were observed </span></span><span style=\"font-family:Verdana;\">to </span><span style=\"font-family:Verdana;\">decrease in blood samples of breast cancer patients
as compared to non-cancer subjects. The results are reliable with other
numerous literature reported studies, the efficiency, and deficiency of these
trace metals may
%K Breast Cancer Blood Samples
%K Invasive Ductal Carcinoma
%K Tumor Stages
%K Essential Elements
%K FAAS
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=110155