%0 Journal Article
%T Bismuth (III) Chloride Catalyzed Multicomponent Synthesis of Substituted Hexahydroimidazo[1, 2-<i>a</i>]Pyridines
%A Noah T. Haskin
%A Richard A. Guingrich
%A Allison J. Schrader
%A Matthew R. Crosse
%A Alpa Y. Dave
%A Eeshwaraiah Begari
%A Ram S. Mohan
%J Green and Sustainable Chemistry
%P 89-95
%@ 2160-696X
%D 2021
%I Scientific Research Publishing
%R 10.4236/gsc.2021.113008
%X The synthesis of <span>nitrogen containing</span> heterocycles is of particular interest in the pharmaceutical industry due to
the range of biological activities exhibited by such compounds. Their synthesis
using multicomponent reactions saves steps and minimizes waste generation. The
bismuth (III) chloride multicomponent synthesis of a series of
hexahydroimidazo[1, 2-</span></span><span><span><span style=\"font-family:&quot;\">&lt;i&gt;</span></span></span><span><span><i><span style=\"font-family:&quot;\">a</span></i></span></span><span><span><i><span style=\"font-family:&quot;\">&lt;/i&gt;</span></i></span></span><span><span><span style=\"font-family:&quot;\">]pyridines is reported. <span>Bismuth (III)
compounds are especially attractive from a green chemistry perspective because
they are remarkably nontoxic, non-corrosive <span>and</span> relatively </span>inexpensive. The reported method avoids chromatography and an
aqueous waste stream to afford the products in a very <span>mass efficient</span> manner.
%K Bismuth Chloride
%K Green Chemistry
%K Heterocycles
%K Multicomponent Reactions
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=111108