%0 Journal Article
%T 邻硝基苯甲醛的制备与谱学分析<br>Preparation and Spectroscopic Analyses of 2-Nitrobenzaldehyde
%A 江雨柔
%A 苏丹
%A 伍林玲
%A 贾爱铨
%A 张千峰
%J Hans Journal of Medicinal Chemistry
%P 1-8
%@ 2331-8295
%D 2022
%I Hans Publishing
%R 10.12677/HJMCe.2022.101001
%X 邻硝基苯甲醛是重要的有机中间体，在有机合成和制药方面有着广泛的应用，本文首先合成N,N’-二甲基甲酰胺二甲基缩醛(DMFDMA)，采用邻硝基甲苯与DMFDMA经缩合氧化合成邻硝基苯甲醛，并通过1H NMR、<sup>13</sup>C NMR、FT-IR等谱学手段对产物进行分析，总收率为88.03%、纯度高达99.07% (HPLC)。本合成生产工艺方法经济成本低，收率高，对环境污染小，相较于传统工艺有较为明显的优势。<br />
2-Nnitrobenzaldehyde is an important organic intermediate, which is widely used in organic syn-thesis and pharmaceutical fields. 2-Nitrobenzaldehyde was synthesized from N,N’-dimethylformamide dimethyl acetal (DMFDMA) by condensation oxidation. The isolated prod-uct was analyzed by 1H NMR, <sup>13</sup>C NMR and FT-IR spectroscopic methods. The total yield was 88.03%, and the purity was as high as 99.07% (HPLC). The synthetic production process has the advantages of low economic cost, high yield and low environmental pollution, and has obvious advantages over the traditional process.
%K 邻硝基苯甲醛，合成，N
%K N’-二甲基甲酰胺二甲基缩醛，生产工艺，环保<br>2-Nitrobenzaldehyde
%K Synthesis
%K N
%K N’-Dimethylformamide Dimethyl Acetal
%K Production Process
%K Environmental Protection
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=48162