%0 Journal Article
%T Febuxostat: Successful Desensitization Protocol
%A Cesar Daniel Alonso-Bello
%A Mayra Mat¨ªas-Carmona
%A Victoria Isabel Castaneda-¨¢vila
%A Evelyn Aranda-Cano
%A Mar¨ªa Isabel Castrej¨®n-V¨¢zquez
%J Open Access Library Journal
%V 9
%N 3
%P 1-5
%@ 2333-9721
%D 2022
%I Open Access Library
%R 10.4236/oalib.1108481
%X Hyperuricemia is defined as the increase in uric acid when it exceeds its solubility limit, about 6.8 mg/dl. Persistent hyperuricemia causes diseases such as gouty arthritis, arthropathy, urolithiasis, and nephropathy. We present the clinical case of a 46-year-old patient with gout and persistent hyperuricemia; he presented cutaneous hypersensitivity to allopurinol and febuxostat and, for this reason, the patient stopped the treatment. After undergoing a 5-day new febuxostat desensitization protocol, he tolerated the drug without adverse effects. This case report highlights the importance of allergy desensitization if there¡¯s no other therapeutic option in patients with hypersensitivity to allopurinol and febuxostat.
%K Febuxostat
%K Drug Allergy
%K Hypersensitivity
%K Desensitization Protocol
%K Allergy
%U http://www.oalib.com/paper/6770655