%0 Journal Article %T Vitamin D and Parathyroid Hormone Profiles in Living Kidney Failure Patients in Côte d’Ivoire %A Maxime Roméo Kouadio %A Lydie Boyvin %A Gnogbo Alexis Bahi %A Assieoussou Jean-Luc N’Guessan %A Cackouoh Carole Constance Koudou %A Souleymane Méité %A Allico Joseph Djaman %J Advances in Biological Chemistry %P 39-47 %@ 2162-2191 %D 2022 %I Scientific Research Publishing %R 10.4236/abc.2022.122004 %X Introduction: Abnormalities in mineral and bone metabolism, particularly phosphocalcic metabolism, are common in renal failure and are associated with a significant morbidity and mortality. The regulation of phosphocalcic metabolism is subject to a particularly precise and complex control of parathormone (PTH) and vitamin D. Assessment of vitamin D and parathyroid hormone concentrations would help to improve the medical management of patients with chronic kidney disease and ensure a better quality of life. Methods: The study population consisted of 138 individuals including 46 non- dialysis renal failure patients, 46 chronic hemodialysis patients and 46 non- renal failure volunteers to serve as controls. Serum Parathyroid hormone and Vitamin D concentrations were measured using the Vidas automated system. Results: 25-hydroxyvitamin D concentrations in controls (65 ± 2.41 nmol/L) and dialysis patients (70 ± 3.03 nmol/L) were significantly higher than those in CKD patients (48 ± 3.34 nmol/L). On the other hand, the mean values of Parathyroid hormone in dialysis patients (312 ± 36.22 pg/mL) and CKD patients (117 ± 10.68 pg/mL) were very high compared to that in controls (25 ± 2.34 pg/mL). Conclusion: Secondary hyperparathyroidism is common in renal failure. Parathyroid hormone and 25-hydroxyvitamin D assays would be adequate for better management of chronic renal failure. %K 25-Hydroxyvitamin D %K Chronic Renal Failure %K Cô %K te d’Ivoire %K Secondary Hyperparathyroidism %K Parathyroid Hormone %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=116127