%0 Journal Article %T Efficacy of Manual Lymphatic Drainage for Breast Cancer-Related Lymphedema %A Na Li %A Qi Wu %A Feng Liu %A Liping Zhang %A Lijuan Zhang %A Qiaoling Zhong %A Huizhen Zhang %J Advances in Breast Cancer Research %P 120-127 %@ 2168-1597 %D 2022 %I Scientific Research Publishing %R 10.4236/abcr.2022.112010 %X Purpose: The effect of manual lymphatic drainage in patients with breast cancer is controversial. The purpose of this study is to evaluate the role of manual lymphatic drainage (MLD) in breast cancer-related lymphedema treatment. Methods: The electronic databases of EMBASE, PubMed, Web of Science, and The Cochrane Library were searched to find English articles on MLD which were published before January 2020. After two evaluators selected the studies and independently evaluated literature quality, meta-analysis was carried out with RevMan 5.3 software. The outcome index of lymphedema treatment changed in edema volume. Results: The study included six RCTs of 364 patients and the meta-analysis showed no significant difference in the effect of MLD for BCRL compared with other treatments (mean difference, 3.76; 95% confidence interval, -35.09 to 42.62; Z, 0.19; p = 0.850). Conclusion: