%0 Journal Article
%T Advances in the Study of Neural Mechanisms Associated with Exercise to Ameliorate Nicotine Addiction
%A Yihan Ni
%A Lin Li
%A Yaqian Qu
%A Siyu Chen
%A Hao Zhang
%A Haoyu Wang
%J Advances in Physical Education
%P 126-141
%@ 2164-0408
%D 2022
%I Scientific Research Publishing
%R 10.4236/ape.2022.122010
%X <b><span style=\"font-family:Verdana;\">Objective:</span></b><span style=\"font-family:Verdana;\"> T</span><span style=\"font-family:Verdana;\">he </span><span style=\"font-family:Verdana;\">o</span><span style=\"font-family:Verdana;\">bjective is to</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> elucidate the effectiveness of exercise as smoking cessation aid by
sorting out the neurotransmitter basis of nicotine addiction and combining it
with the neurotransmitter modulation effect of exercise, and finally to
organize and analyze the mechanisms related to exercise to ameliorate nicotine
addiction. </span><b><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"font-family:Verdana;\"> We searched the Web of Science and PubMed da</span><span style=\"font-family:Verdana;\">tabases for keywords, including ¡°nicotine
addiction¡±, ¡°exercise¡±, ¡°sports¡±, </span><span style=\"font-family:Verdana;\">¡°phys</span><span style=\"font-family:Verdana;\">ical
activity¡±, ¡°smoking cessation¡± and ¡°tobacco withdrawal¡±, and compiled</span><span style=\"font-family:Verdana;\"> and analyzed the relevant literature to explain the neurobiological mechanisms
of nicotine addiction and the effects of exercise on ameliorat</span></span><span style=\"font-family:Verdana;\">ing</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> nicotine addic</span><span><span style=\"font-family:Verdana;\">tion and related
mechanisms. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> 1) long-term nicotine intake, on the</span></span><span style=\"font-family:Verdana;\"> one </span><span style=\"font-family:Verdana;\">hand, binds to acetylcholine receptors to produce
rewarding effects, and on </span><span style=\"font-family:Verdana;\">the other
hand</span></span><span style=\"font-family:Verdana;\">,</span><span style=\"font-family:Verdana;\"> causes rewarding effects by regulating the release
of various</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> neuro</span><span style=\"font-family:Verdana;\">transmitters
and signaling, making smokers feel pleasure and experiencing</span><span style=\"font-family:Verdana;\"> with</span><span style=\"font-family:Verdana;\">drawal symptoms after stopping smoking; 2)
exercise can effectively amelio</span><span style=\"font-family:Verdana;\">ra</span></span><span style=\"font-family:Verdana;\">te</span><span style=\"font-family:&quot;\"> <span style=\"font-family:Verdana;\">nicotine addiction; 3) exercise
%K Nicotine Addiction
%K Reward Effect
%K Smoking Cessation
%K Acetylcholine
%K Midbrain Limbic Dopamine
%K Withdrawal Response
%K Exercise
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=116744