%0 Journal Article
%T Patient and Health System Factors Associated with First Line Tuberculosis Treatment Adherence, 2009-2014
%A Gifty Adu
%A Bernice N. Harris
%A Andy Beke
%J Journal of Tuberculosis Research
%P 220-229
%@ 2329-8448
%D 2022
%I Scientific Research Publishing
%R 10.4236/jtr.2022.104017
%X <b><span style=\"font-family:Verdana;\">Background</span></b><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">: The prevalence and incidence rate of tuberculosis
remains high although the disease is known to be almost always curable provided
the patient adheres to the treatment regimen. This study assessed the strength
of association between known patient and health system factors associated with
first line tuberculosis treatment adherence. </span><b><span style=\"font-family:Verdana;\">Methods</span></b><span style=\"font-family:Verdana;\">: A quantitative
cross sectional study. Retrospective chart review</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">s</span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> were conducted among 570 persons who had primary
tuberculosis and received first line treatment at a health facility within the
Nkangala district, Mpumalanga province and who had a treatment outcome recorded
between 1st January 2009 </span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">and</span></span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> 31st December 2014. Adherence to first line tuberculosis
treatment was defined as taking ¡Ý80% of tuberculosis prescribed drugs within a
period of 6 to 8 months. Stata software (logistic regressions model) was used
to analyze results and find the strength of association between known factors
and treatment adherence. </span><b><span style=\"font-family:Verdana;\">Results</span></b><span style=\"font-family:Verdana;\">: Out of the 570 study par</span><span style=\"font-family:Verdana;\">ticipants, 473 were adherent and 96 were not
adherent. There was a statistically significant association between age 18
years and above (OR: 1.02, P</span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">-</span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">value: 0.027), sex (lower in
males OR: 0.44, P-value: 0.001) and support (OR: 3.04, P-value: 0.05) and</span></span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> HIV (OR: 1, P-value: 0.634) and first line TB
treatment adherence. </span><b><span style=\"font-family:Verdana;\">Conclusion</span></b> <b><span style=\"font-family:Verdana;\">and</span></b> <b><span style=\"font-family:Verdana;\">Recommendation</span></b><span style=\"font-family:Verdana;\">:
&gt;80% adherence to
%K Adherence
%K First-Line
%K Tuberculosis
%K Treatment
%K Non-Adherence
%K Health System Factors
%K Patient
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=122009