%0 Journal Article
%T Antimicrobial Resistance of <i>Pseudomonas aeruginosa</i> Isolated from Human Infections in N¡¯Djamena, Chad
%A Ahmat Mahamat Ahmat
%A Mahamat Ali Bolti
%A Fissou Henry Yandai
%A Hamit Mahamat Alio
%A Martin-Paul Baane
%A Mayor¨¦ At¨¦ba Djibrine
%A Evariste Bako
%A Nicolas Barro
%A Choua Ouchemi
%J Open Journal of Medical Microbiology
%P 17-30
%@ 2165-3380
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojmm.2023.131002
%X <b><span style=\"font-size:10.0pt;font-family:&quot;\">Background:</span></b><span style=\"font-size:10.0pt;font-family:&quot;\"> Urinary Tract infections and pus are major public health problems. The
evolution of bacterial resistance to antibiotics makes the treatment of these
infections problematic. This is why this study is undertaken to identify and
evaluate the resistance of <i>Pseudomonas</i> <i>aeruginosa</i> to antibiotics. <b>Methods:</b> This is a
prospective study carried out from December 2020 to November 2021. The germs
were isolated on the agar supplemented with cetrimide and identified by the API
20 NE gallery method according to the manufacturer¡¯s protocol. The strains¡¯
resistance profiles were determined by the diffusion method on Mueller-Hinton
according to the criteria EUCAST-</span><span style=\"font-size:10.0pt;font-family:&quot;\"> </span><span style=\"font-size:10.0pt;font-family:&quot;\">2021. <b>Results:</b> A total of 46/1467 (3.13%) <i>Pseudomonas</i> <i>aeruginosa</i> were identified, </span><span style=\"font-size:10.0pt;font-family:&quot;\">of which 29/1008 (2.87%) were urinary tract infections and 17/459 (3.70%)
were pus. The high resistances were: 97.8% to ceftazidim, 91.3% to aztreonam,
93.5% to cefepim, 82.6% to piperacillin, 58.7% to levofloxacin, 52.2% to
amikacin, 47.8% to tazobactam-piperacillin, 47.8% to tobramycin and 43.5% to
ciprofloxacin. Low resistance was only 2.2% to fosfomycin, 2.2% to colistin and
15.2% to imipenem. <b>Conclusion:</b> This study reveals the considerable
resistance of <i>Pseudomonas</i> <i>aeruginosa</i> to commonly used antibiotics, and thus compromises the empirical treatment
practiced in hospitals. This result motivates the need to carry out
susceptibility testing of isolates before any prescription of antimicrobials.</span>
%K &lt
%K i&gt
%K Pseudomonas aeruginosa&lt
%K /i&gt
%K Resistance to Antibiotics
%K Urine
%K Pus
%K N¡¯Djamena
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=122673