%0 Journal Article
%T Physico-Chemical and Mineralogical Characterizations of Tchiky Clays (Thies, Senegal) for Pharmaceutical Uses
%A Rokhaya Sylla Gueye
%A Nango Gaye
%A Ousmane Ka
%A Mamadou Bald¨¦
%A Adama Diedhiou
%A Ngon¨¦ Diouf
%A Samba F. Ndoye
%A Idrissa Ndoye
%A Yoro Tine
%A Rokhaya Gueye
%A Mouhamadou B. Diop
%A Matar Seck
%A Djibril Fall
%A Alassane Wel¨¦
%J Journal of Minerals and Materials Characterization and Engineering
%P 36-48
%@ 2327-4085
%D 2023
%I Scientific Research Publishing
%R 10.4236/jmmce.2023.112004
%X Our study focused on the valuation of Tchiky clays. This work aims to evaluate its properties to explore possible uses in pharmacy. Physico-chemical and mineralogical characterizations were carried out, as well as pharmacopoeial tests and an evaluation of the antioxidant activity. Thus, chemical analysis by X-ray fluorescence spectrometry gave silicon (55.65%), iron (15.73%), aluminum (13.53%), potassium (6.05%), titanium (3.98%), magnesium (2.10%), and calcium (0.82%). X-ray diffraction showed the presence of kaolinite, quartz and illite. This study also revealed that the sample studied was essentially a plastic clay of hard consistency, with average flowability. The evaluation of the antioxidant activity gave a percentage inhibition of 62.97% for a concentration of 7.5 g/l with an IC50 of 5.5 g/l. These results should allow use as an excipient in pharmacy, particularly in liquid, semi-liquid and pasty formulations.
%K Clays
%K Tchiky
%K Minerals
%K Pharmacopoeia
%K Antioxidant Activity
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=123976