%0 Journal Article %T Esophagogastric Reconstruction in Cobra-Head Shape with Toupet-Like Partial Anti-Reflux Technique for Resection of Proximal Gastric Tumors. Experience with Three Cases from a Non-Asian Population %A Alberto M. Le¨®n-Takahashi %A Ana P. Mel¨¦ndez-Fern¨˘ndez %A Leonardo S. Lino-Silva %A Horacio N. L¨®pez-Basave %A Rosa Angelica Salcedo Hernandez %A C¨¦sar Zepeda-Najar %A ¨˘ngel Herrera-G¨®mez %J Open Journal of Gastroenterology %P 149-160 %@ 2163-9469 %D 2023 %I Scientific Research Publishing %R 10.4236/ojgas.2023.134016 %X Background: Proximal gastrectomy is a rarely performed procedure but a feasible option in benign tumors and malignant neoplasms in the proximal third of the stomach since novel options of reconstructions are available nowadays with fewer long-term sequels. Methods: Report of three cases of proximal gastric gastrointestinal stromal tumors (GIST), with a description of its presentation, histological characteristics, and follow-up after being treated with proximal gastrectomy with cobra head reconstruction. Results: Case 1: A 62-year-old woman with epigastric pain of four months with endoscopic evidence of a cardia GIST. The surgery was performed without complications. The histopathological report confirmed a fusiform GIST of 3.2 ˇÁ 3 ˇÁ 2.5 cm, stage IA. No adjuvant treatment was considered. An esophagogram showed no evidence of reflux and no stenosis, and no disease recurrence after 40-months follow-up. Case 2: A 66-year-old woman with dyspepsia and a palpable tumor in the epigastrium. The surgery was performed without complications. The pathology report confirmed a proximal gastric GIST of 13 ˇÁ 8 ˇÁ 7 cm, staged II. She received adjuvant treatment with imatinib for 36 months without recurrence and no reflux or stenosis. Case 3: A 55-year-old woman with intermittent hematemesis and right subscapular pain. The surgery was performed without complications. The histopathological report concluded that a GIST tumor of the cardia, 1.4 ˇÁ 1.2 cm, staged IA. She was left in observation. At a 6-month follow-up, she does not report dysphagia, reflux, or stenosis, and no locoregional recurrence. Conclusions: Open and laparoscopic proximal gastrectomy is a safe therapeutic option for GIST. Furthermore, the reconstruction of the esophagus-gastro anastomosis in the cobra head after proximal gastrectomy is feasible and secure in our population, with good functional results in a short follow-up. %K GIST %K Gastric Cancer %K Laparoscopy %K Proximal Gastrectomy %K Cobra Head Reconstruction %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=124376