%0 Journal Article
%T Risk Factors for COVID-19 Related Death during the First Three Waves of the Pandemic in an Epidemic Treatment Center at Dakar, Senegal
%A Moustapha Diop
%A Papa Samba Ba
%A Viviane Marie Pierre Cisse
%A Nd¨¨ye Aissatou Lakhe
%A Betty Fall
%A Moustapha Lo
%A Ndong Essomba
%A Bruce Wembulua
%A Fatimata Wone
%A Becaye Fall
%A Khardiata Diallo-Mbaye
%A Daye Ka
%A Louise Fortes
%A Ousmane Faye
%A Ndongo Dia
%A Khalifa Ababacar Wade
%A Abdou Rajack Ndiaye
%A Amadou Alpha Sall
%A Moussa Seydi
%A Mame Thierno Dieng
%J Advances in Infectious Diseases
%P 117-131
%@ 2164-2656
%D 2023
%I Scientific Research Publishing
%R 10.4236/aid.2023.132013
%X <strong>Introduction-Objective:</strong> COVID-19 is a highly transmissible but often mild viral infection. However, some patients can present severe COVID-19 and subsequently die. The aim of the present study was to assess the risk factors for COVID-19 related death during the first three waves of the disease at the Epidemic Treatment Center (ETC) of Dakar Principal Hospital (DPH). <strong>Method:</strong> We conducted a descriptive and analytical perspective survival study from April 4, 2020 to September 25, 2021, including adult patients with COVID-19, hospitalized at the ETC of DPH. Log Rank test and multivariate Cox model were performed to identify risk factors for death. <strong>Results:</strong> We included 556 COVID-19 patients with mean age of 57 <span style=\"white-space:nowrap;\">&amp;#177;</span> 17 years and a male-to-female ratio of 1.26. The number of deaths during one month of follow-up was 41, representing a cumulative risk of 7.4%. The log Rank test showed that being from the third wave (p = 0.0056), advanced age (p = 0.00098), presence of at least one comorbidity (p = 0.034), High blood pressure (p = 0.024), d-dimer level ¡Ý 1000 IU/L (p &lt; 0.001) and CRP level ¡Ý 12 mg/L (p = 0.014) appeared to be risk factors for death. In multivariate Cox regression, the third wave of the pandemic (HR = 2.25; 95% CI [1.08 - 4.68], p = 0.03) and advanced age (HR = 2.68; 95% CI [1.23 - 5.85], p = 0.013) were risk factors for death. <strong>Conclusion:</strong> Our study showed that elderly and third-wave of COVID-19 patients were more at risk to die. Knowledge of risk factors for COVID-19 related death could improve the prognosis of these patients.
%K COVID-19
%K Waves
%K Death
%K Risk Factors
%K Dakar
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=124714