%0 Journal Article
%T 2型DKD患者血清焦亡相关蛋白与肾损伤的分析<br> Analysis of Serum Pyrodeath Re-lated Proteins and Renal Injury in Patients with Type 2 DKD
%A 马茹洁
%A 巴应贵
%J Asian Case Reports in Emergency Medicine
%P 53-58
%@ 2328-0395
%D 2023
%I Hans Publishing
%R 10.12677/ACREM.2023.112009
%X 糖尿病肾病(DKD)是糖尿病最常见的并发症之一，也是导致终末期肾病的主要原因。全球30%~40%糖尿病患者因病情迁延而进展至DKD，伴有终末期肾病的患者五年生存率 &lt; 20%。因此，延缓DKD进展对于改善患者生存质量具重大意义。目前研究发现，2型DKD发病进展中的无菌性炎症机制与病情进展密切相关。<br />
Diabetic nephropathy (DKD) is one of the most common complications of diabetes and the main cause of end-stage renal disease. Globally, 30%~40% of diabetic patients progress to DKD due to disease delay, and the five-year survival rate of patients with end-stage re-nal disease is less than 20%. Therefore, delaying DKD progression is of great significance for im-proving patients’ quality of life. Current studies have found that the aseptic inflammatory mecha-nism in the progression of type 2 DKD is closely related to the progression of the disease.
%K 2型糖尿病肾病，细胞焦亡，NLRP3炎症小体，肾损伤<br> Type 2 Diabetic Nephropathy
%K Pyrocytosis
%K NLRP3 Inflammasome
%K Renal Injury
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=66303