%0 Journal Article
%T Pleural Fluid Alkaline Phosphate Levels to Differentiate between Tuberculosis and Malignant Pleural Effusion a Tertiary Care Experience
%A Syed Abdul Waheed
%A Afshan Nisar
%A Amanullah Lail
%A Ghulamullah Lail
%A Muhammad Imran
%A Javid Ali
%A Mahboob Ali
%A Kamran Khan
%A Nadeem Rizvi
%J Journal of Tuberculosis Research
%P 86-94
%@ 2329-8448
%D 2023
%I Scientific Research Publishing
%R 10.4236/jtr.2023.112009
%X <span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Introduction: </span></b></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">Pleural effusion (PF) is a common clinical presentation in several
diseases. Tuberculosis is one of the most frequent causes of exudative pleural
effusions in immunocompetent patients. Tuberculosis is the leading cause of
morbidity and mortality from an infectious disease in developing countries.
Pakistan is ranked fifth in the world in terms of tuberculosis high-burden
countries. Various pleural fluid parameters have been used to identify the
cause of pleural effusion. It has been discovered that tuberculous pleural
effusions had a greater alkaline phosphatase (ALP) concentration than
transudative effusions. This study used pleural fluid alkaline phosphatase
levels to distinguish between tuberculous pleural effusion and malignant
pleural effusion because there is little information from tuberculosis-high
burden </span><span><span style=\"font-family:Verdana;\">nations like Pakistan. </span><b><span style=\"font-family:Verdana;\">Study
Design</span></b></span></span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">:</span></b></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> A descriptive cross-sectional study cond</span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">ucted at the Jinnah Postgraduate Medical Center in Karachi between
October 2016 and October 2017. </span><b><span style=\"font-family:Verdana;\">Material and Methods: </span></b><span style=\"font-family:Verdana;\">The study comprised
all patients who were admitted to the department of chest medicine at Jinnah
post graduate medical centre (JPMC) of either gender</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">between
the ages of 18 and 70 who had exudative lymphocytic pleural effusions lasting
two weeks or more </span><span style=\"font-family:Verdana;\">included in the study. Non
probability consecutive sampling was used to co</span><span style=\"font-family:Verdana;\">llect data. Patients who
have tonsillitis, pharyngitis, pneumonia, asthma, Chronic obstructive pulmonary
disease (COPD), or a history of hemoptysis, Bleeding disorders like, platelet
function disorder,
%K Pleural Fluid (PF)
%K Alkaline Phosphatase (ALP)
%K Tuberculosis
%K Malignant
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=125997