%0 Journal Article %T Fundamental Concepts behind the Development of Gamma-Ray, Directed Energy Sources %A Eugene Oks %J Open Journal of Microphysics %P 27-35 %@ 2162-2469 %D 2023 %I Scientific Research Publishing %R 10.4236/ojm.2023.133003 %X We discuss novel advanced concepts suitable for the practical design of gamma-ray sources of directed energy. One concept is based on the self-channeling of a powerful optical laser in a gas within a metal tube. Another concept employs a direct excitation of a quadrupole nuclear level by a powerful optical laser. The third concept is based on the process of a high-order harmonic generation by an x-ray laser. All three concepts can be used for designing gamma-ray lasers that would have significant advantages over x-ray lasers. First, missile defense systems employing gamma-ray lasers would be weather independent. Second, the gamma-ray laser radiation can penetrate through the sand, which could be suspended in the air in a desert either naturally (due to strong winds) or artificially (as a protective ˇ°shieldˇ±). Besides, the first out of the three concepts can beemployed for creating non-laser gamma-ray sources of directed energy to be used for detecting stored radioactive materials, including the radioactive materials carried by an aircraft or a satellite. Last but not least: these concepts can be also used for remotely destroying biological and chemical weapons as a preemptive strike or during its delivery phase, as well as for distinguishing a nuclear warhead from decoy warheads. Thus, the defense capabilities of the proposed gamma-ray lasers can save numerous lives. %K Gamma-Ray Lasers %K Directed Energy Sources %K Self-Channeling %K Quadrupole Nuclear Levels %K High-Order Harmonic Generation %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=126272