%0 Journal Article %T Immediate Respiratory Response to Electronic Cigarette Use %A Jake Morales %A Jafar Vossoughi %A Arthur T. Johnson %A Maria V. Bautista %J Open Journal of Respiratory Diseases %P 35-47 %@ 2163-9418 %D 2023 %I Scientific Research Publishing %R 10.4236/ojrd.2023.133004 %X Background: Electronic cigarettes were originally designed to reduce adult dependency on normal cigarettes and as a tobacco cessation tool to substitute traditional cigarettes. But it has become the most popular among teenagers. Rationale: To investigate the immediate adverse respiratory effect of short-term electronic cigarette vapor inhalation. Method: Twenty-five subjects were randomly selected and used in this study. The respiratory resistance values were evaluated and used for comparison. The subjects were asked to breathe into the Airflow Perturbation Device (APD) for evaluation of their respiratory resistance before vaping (in triplicate). The same subjects, a minute later, were then asked to use one poke (3 seconds) of the e-Cigarette device to inhale e-Cigarette vapor with nicotine from a pod with 59 mg/ml nicotine. Immediately following the e-Cigarette use, their respiratory resistance was measured again (in triplicate). Results: Comparing the respiratory resistance values before and immediately after exposure to e-Cigarette vapor showed that their respiratory resistance increased almost immediately. Conclusion: Although there are long-term studies showing that the e-Cigarette is as harmful as regular cigarettes, this study showed a nearly immediate effect of using the e-Cigarette that significantly increased the respiratory resistance of the user. Very short exposure time to e-Cigarette vapor (3 seconds only), caused an immediate adverse physiologic effect in respiratory resistance. %K E-Cigarette %K Respiratory Resistance %K JUUL %K E-Cigarette Vapor %K Nicotine Pod %K Airflow Perturbation Device (APD) %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=126848