%0 Journal Article
%T Impact of Lutein-Based Food Supplement on Macular Pigment, Glare and Contrast Vision
%A Peter Sutter
%J Open Journal of Ophthalmology
%P 316-326
%@ 2165-7416
%D 2023
%I Scientific Research Publishing
%R 10.4236/ojoph.2023.133030
%X <strong>Purpose:</strong> To evaluate the impact of a specially formulated food supplement containing 20 mg free lutein and 2.8 mg zeaxanthin on macular pigment volume (MPV) and visual function. <strong>Methods:</strong> In this prospective non-comparative study healthy subjects were instructed to take one capsule of Eagle Eye Lutein 20 Vision Caps (Innomedis AG) per day with a meal for 6 months. MPV was measured with the MP-Eye system (AzulOptics) after 3 and 6 months of treatment. Mesopic vision (MV), glare sensitivity (GS) and contrast vision threshold (CVT) were measured with the Binoptometer 4P system (OCULUS Optikger<span style=\"white-space:nowrap;\">&amp;#228;</span>te). <strong>Results:</strong> Twenty-three healthy subjects between 19 and 56 years were enrolled. A significant increase was observed in MPV (p &lt; 0.001), with associated improvements in MV level (p = 0.042), GS (p = 0.009) and CVT (p = 0.036). Mean changes in MPV, MV level, GS and CVT were 2.2 ¡À 1.7, 0.4 ¡À 0.8, 0.4 ¡À 0.7, and -9.3% ¡À 16.1%, respectively. The change in MV (r = -0.628, p = 0.002), GS (r = -0.778, p &lt; 0.001) and CVT (r = -0.625, p = 0.002) with treatment was found to correlate significantly with their corresponding baseline values. <strong>Conclusions:</strong> The specially formulated food supplement containing lutein and zeaxanthin induced a significant increase in MPV, and consequently an improvement in the visual function after 3 and 6 months in healthy subjects.
%K Macular Pigment
%K Mesopic Vision
%K Glare Disability
%K Contrast Sensitivity
%K Lutein
%K Zeaxanthin
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=127197