%0 Journal Article
%T Gynecological Side Effects of Tamoxifen among Sudanese Women, Khartoum, Sudan, 2020
%A Mawahib Ahmed Elawad Abu Elgasim
%A Yousra Abdelmoniem Suleiman
%A Lobaina Abozaid
%A Dlal Alser Hassan Mohmmed
%A Soha Saad Aldin Mohamad Suliman
%A Duaa Hamd Abdulatif Farh
%J Advances in Breast Cancer Research
%P 152-162
%@ 2168-1597
%D 2023
%I Scientific Research Publishing
%R 10.4236/abcr.2023.124012
%X <strong>Background</strong><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"><strong>:</strong> In Sudan, the common endocrine therapy tamoxifen is prescribed to HR-positive
patients, which is associated with a variety of complications such as hot
flashes, vaginal discharge, and vaginal dryness. </span><b><span style=\"font-family:Verdana;\">Objective</span></b><span style=\"font-family:Verdana;\">: This study
aimed to determine the gynecological side effects of tamoxifen among Sudanese
women who have been diagnosed with breast cancer in Khartoum, Sudan. </span><b><span style=\"font-family:Verdana;\">Methods</span></b><span style=\"font-family:Verdana;\">:
A retrospective cross-sectional study was conducted at Alzara Hospital in Al
Amal Toure Revere, Sudan. A convenience sample of individuals previously
diagnosed with breast cancer attended refer clinic. From October 2020 to
September 2021, all patients attending were checked for eligibility. </span><b><span style=\"font-family:Verdana;\">Results</span></b><span style=\"font-family:Verdana;\">:
A total of 100 patients were enrolled in the study; 60% of patients reported
increased vaginal secretions after taking the drug, 28% reported normal vaginal
secretions with no change, and 11% reported decreased secretions after taking
the medication, while 22% developed vaginal bleeding, and 22% of the ultrasound
results revealed endometrial masses among the study patients. Also, 54 percent
of female patients experienced hot flashes after taking the medication, and 12%
of women missed some doses of treatment. </span><b><span style=\"font-family:Verdana;\">Conclusion</span></b><span style=\"font-family:Verdana;\">: Tamoxifen results
in several gynecological side effects in women with breast cancer. A high
percentage of women in the study developed hot flashes, vaginal bleeding, and
discharge, in addition to having ultrasound results showing endometrial masses
among them.</span></span></span></span>
%K Tamoxifen
%K Breast Cancer
%K Gynecological Side Effects
%K Sudanese Women
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=128380