%0 Journal Article
%T Contribution of Automated Antigen Tests, the LumiraDx Ag Test in the Response during the Second Wave of the COVID-19 Pandemic in Bangui
%A Clotaire Donatien Rafa£¿
%A Pierre Somse
%A Wilfrid Sylvain Nambei
%A Ernest Lango-Yaya
%A Marie-Roseline Darnycka Belizaire
%A Ulrich Vickos
%A Narcisse Patrice Komas
%A Oscar Senzongo
%A Luc Salva Heredeibona
%A Ulrich Jeffrey Kotemossoua
%A Rabbi Mermoz Senekian
%A Simon Pounguinza
%A Jepht¨¦ Estim¨¦ Kaleb Kandou
%A Christian-Diamant Mossoro-Kpinde
%A Laurent B¨¦lec
%A Jean De Dieu Longo
%A Norbert Richard Ngbale
%A Abdoulaye Sepou
%A Fran£¿ois-Xavier Mbopi-Keou
%A G¨¦rard Gr¨¦senguet
%A Boniface Koffi
%J Journal of Tuberculosis Research
%P 173-183
%@ 2329-8448
%D 2023
%I Scientific Research Publishing
%R 10.4236/jtr.2023.114017
%X <b><span style=\"font-family:Verdana;\">Context</span></b><span style=\"font-family:&quot;\"> <b><span style=\"font-family:Verdana;\">and</span></b> <b><span style=\"font-family:Verdana;\">objective:</span></b><span style=\"font-family:Verdana;\"> The COVID-19 pandemic has become a major
public health problem and has mobilized many innovative means of diagnosis. The
Central African Republic is not spared. The emergence of variants and their
impact require health monitoring despite the obligation of vaccination. The </span><span style=\"font-family:Verdana;\">purpose of this campaign was to determine the
circulation of pending s</span><span style=\"font-family:Verdana;\">econd-wave variants. </span><b><span style=\"font-family:Verdana;\">Patients</span></b> <b><span style=\"font-family:Verdana;\">and</span></b> <b><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"font-family:Verdana;\"> A second mass screening campaign took place from 02 to 22 July 2021 in the main
land and river entry points of Bangui (Exit North-PK12, Exit South-PK9, Port
Beach) and at the LNBCSP. Antigenic and RT-PCR tests carried out on
nasopharyngeal samples made it possible to select strains which were finally
sequenced. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> Of 2687 participants included in the study, 53
(1.97%) were positive for SARS-CoV-2. Thirteen (1.53%) were male and 40 (2.18%)
female. The analy</span></span><span style=\"font-family:Verdana;\">se</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">s</span><span style=\"color:red;\"> </span><span style=\"font-family:Verdana;\">carried out on the LumiraDx analyzer
were positive for 109 samples against 53 on the RT-PCR. The prevalence was
higher in the most tested age groups (30 to 50 years) with two clusters
identified. B.1.617.2 (Delta) variants were predominant (57%). </span><b><span style=\"font-family:Verdana;\">Conclusion:</span></b><span style=\"font-family:Verdana;\"> SARS-CoV-2 continues to circulate. The acquisition of automated antigenic tests
(LumiraDx&amp;#174) with sensitivity and specificity close to those of the
reference test (RT-PCR) will allow better mass diagnosis for an optimization of
the surveillance of COVID-19 in our countries with limited resources. The
predominance of the B.1.617.2 (Delta) variant would suggest a third wave in the
Central African Republic.
%K COVID-19
%K Automated Antigen Testing
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=130171