%0 Journal Article
%T Adverse Pregnancy Outcomes Following Cryotherapy, Thermal Ablation and Loop Electrosurgical Excision Procedure for Cervical Intraepithelial Neoplasia Treatment: A Pilot Study among Zambian Women
%A Victoria Mwiinga-Kalusopa
%A Johanna E. Maree
%A Concepta Kwaleyela
%A Patricia Katowa-Mukwato
%J Open Journal of Obstetrics and Gynecology
%P 7-17
%@ 2160-8806
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojog.2024.141002
%X <strong>Background:</strong> <span style=\"font-family:Verdana;\">Cervical Intraepithelial neoplasia treatments have become essential
interventions to manage cervical lesions</span><span style=\"font-family:Verdana;\">. </span><span style=\"font-family:Verdana;\">Majority of the recipients of these treatments are
women within the reproductive age group, who according to literature may</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">be at risk of adverse
pregnancy outcomes</span><span style=\"font-family:Verdana;\">. This pilot study is part
of </span><span style=\"font-family:Verdana;\">a</span><span style=\"font-family:Verdana;\"> study investigating adverse pregnancy outcomes
among women who received Cryotherapy, Thermal ablation and Loop Electrosurgical
Excision Procedure compared to the untreated women in Zambia. </span><b><span style=\"font-family:Verdana;\">Materials and Methods: </span></b><span style=\"font-family:Verdana;\">This descriptive study analyzed records of 886 (n</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">=</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">443
treated and n</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">=</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">443 untreated)</span><span style=\"font-family:&quot;\"> </span><span style=\"font-family:Verdana;\">women aged 15 </span><span style=\"font-family:Verdana;\">-</span><span style=\"font-family:Verdana;\"> 49 years. The women were
either screened with Visual Inspection with Acetic Acid or treated for Cervical
Intraepithelial neoplasia at the Adult Infectious Disease Centre between
January 2010 and December 2020. Women meeting the criteria were identified
using the Visual Inspection with Acetic Acid screening records and telephone
interviews to obtain the adverse pregnancy outcome experienced. </span><span style=\"font-family:Verdana;\">Data w</span><span style=\"font-family:Verdana;\">ere</span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> analysed using STATA
version 16 to determine the prevalence and obtain frequency distribution of
outcomes of interest. Univariate and multivariable binary logistic regression
estimated odds of adverse pregnancy outcomes across the three treatments. </span><b><span style=\"font-family:Verdana;\">Results: </span></b></span><span style=\"font-family:Verdana;\">The respondents were</span><span style=\"font-family:&quot;\">
%K Adverse Pregnancy Outcomes
%K Cervical Intraepithelial Neoplasia
%K Cryothera-py
%K Thermal Ablation
%K Loop Electrosurgical Excision Procedure
%K Pilot
%K Repro-ductive Age
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=130408