%0 Journal Article
%T 扶正祛邪滋阴汤结合放化疗治疗三阴性乳腺癌的临床评价<br>Clinical Evaluation of Fuzhengquxieziyin Decoction Combined with Radiotherapy and Chemotherapy in the Treatment of Triple Negative Breast Cancer
%A 赵东
%A 斯晓芳
%A 苟小琳
%A 齐萌
%J World Journal of Cancer Research
%P 7-12
%@ 2164-9057
%D 2024
%I Hans Publishing
%R 10.12677/WJCR.2024.141002
%X 目的：探索扶正祛邪滋阴汤结合放化疗治疗三阴性乳腺癌的临床疗效。方法：自2020年1月至2023年10月选取48例经手术、放疗及化疗后的II至III期三阴性乳腺癌患者，采取随机、双盲、自愿的原则分成两组。治疗组采取扶正祛邪滋阴汤内服8周，对照组采取安慰剂(维生素C)内服8周。入组前均给与CT、彩超及肿瘤标记物检查，治疗结束后再给予彩超及肿瘤标记物检查，之后每3个月随访1次，1年后定期给与CT、彩超及肿瘤标记物检查，随访期共3年。结果：治疗组24例三阴性乳腺癌患者采取扶正祛邪滋阴汤内服治疗后，第1年，23例无复发及转移，1例复发，0例转移。总有效率为95.8%。第2年，22例无复发及转移，1例复发，1例转移。总有效率为91.6%。第3年，20例无复发及转移，1例复发，3例转移。总有效率为83.3%。对照组24例三阴性乳腺癌患者采取安慰剂(维生素C)内服，第1年，22例无复发及转移，1例复发，1例转移。总有效率为91.6%。第2年，19例无复发及转移，1例复发，4例转移。总有效率为79.2%。第3年，16例无复发及转移，2例复发，6例转移。总有效率为66.7%。结论：扶正祛邪滋阴汤结合放化疗治疗三阴性乳腺癌的临床疗效肯定，患者复发及转移率低，值得推广。<br />
Objective: To explore the clinical effect of Fuzhengquxieziyin Decoction combined with radiotherapy and chemotherapy in the treatment of triple-negative breast cancer. Methods: From January 2020 to October 2023, 48 patients with stage II to III triple negative breast cancer after surgery, radio-therapy and chemotherapy were randomly, double-blind and voluntarily divided into two groups. The treatment group took Fuzhengquxieziyin decoction for 8 weeks, and the control group took placebo (vitamin C) for 8 weeks. CT, color Doppler ultrasound and tumor markers were examined before enrollment, and then color Doppler ultrasound and tumor markers were examined after treatment. After that, CT, color Doppler ultrasound and tumor markers were followed up every 3 months, and CT, color Doppler ultrasound and tumor markers were examined regularly 1 year later. The follow-up period was 3 years. Results: In the treatment group, 24 patients with triple- negative breast cancer were treated with Fuzhengquyeziyin Decoction, 23 cases had no recurrence or metastasis, 1 case had relapse and 0 cases had metastasis in the first year. The total effective rate was 95.8%. In the second year, 22 cases had no recurrence or metastasis, 1 case had relapse and 1 case had metastasis. The total effective rate was 91.6%. At the 3rd year, 20 cases had no recurrence or metastasis, 1 case had relapse and 3 cases had metastasis. The total effective rate was 83.3%. In the control group, 24 patients with triple-negative breast cancer took placebo (vitamin C) orally. In the first year, 22 cases had no recurrence or metastasis, 1 case had recurrence and 1 case had metastasis. The total effective rate was 91.6%. In the second year, 19 patients had no recurrence or metastasis, 1 had relapse and 4 had metastasis. The total effective rate was 79.2%. At the 3rd year, 16 cases had no recurrence or metastasis, 2 cases had relapse and 6 cases had metastasis. The total effective rate was 66.7%. Conclusion: Fuzhengquyeziyin Decoction combined with chemoradiotherapy has definite
%K 扶正祛邪滋阴汤，三阴性乳腺癌，有效率<br>Fuzhengquxieziyin Decoction
%K Triple Negative Breast Cancer
%K Effective Rate
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=78976