%0 Journal Article
%T COVID-19/Tuberculosis Co-Infection at the Epidemic Treatment Center (ETC) of Saint-Louis (Senegal): About 9 Cases
%A Alassane Di¨¨ye
%A Moustapha Diedhiou
%A Papa Latyr Junior Diouf
%A Mba Bambo Diakhaby
%A Demba Makalou
%A Samba Niang
%A Diatou Dia-Gueye
%A Amadou Diop Dia
%A Ibrahima Louis Martin Dieng
%A Seynabou L£¿
%A Nd¨¦ye M¨¦ry Dia-Badiane
%J Advances in Infectious Diseases
%P 56-66
%@ 2164-2656
%D 2024
%I Scientific Research Publishing
%R 10.4236/aid.2024.141005
%X <strong>Introduction: </strong>COVID-19 is a global public health emergency that can cause acute respiratory distress syndrome. In countries where tuberculosis (TB) is endemic, coinfection of COVID-19 and TB is often encountered, which increases the risk of developing severe forms of COVID-19. <strong>Objectives: </strong>The aim of this study was to determine the prevalence of COVID-19/TB coinfection at the Epidemic treatment center (ETC) in Saint-Louis (Senegal) and to describe the epidemiological, clinical, paraclinical, and outcome profile of co-infected patients. <strong>Patients and Methods</strong>: This is a retrospective, cross-sectional, descriptive cohort study based on the records of COVID-19/ TB co-infected patients who were hospitalized at the ETC in Saint-Louis (Senegal) over an 18-month period from March 2020 to September 2021. <strong>Results:</strong> Out of a total of 454 hospitalizations, we collected records of 9 patients co-infected with COVID-19/TB, resulting in a prevalence of 2%. The study included patients with a median age of 34 years (range: 10-86 years), with a male predominance (7 cases) and a sex ratio of 3.5. The majority of patients (88.9%) had severe forms of COVID-19. Dyspnea and cough were reported in all patients (100%). Pulmonary TB was the most frequent localization, with 9 cases. The diagnosis of COVID-19 was confirmed by nasopharyngeal PCR in all patients (100%). Bacilloscopy was positive in 3 out of 5 cases. One patient tested positive for GeneXpert<span style=\"white-space:nowrap;\"><sup>?</sup></span> MTB/RIF without rifampicin resistance. All patients were prescribed the hydroxychloroquine-azithromycin combination and anti-tuberculosis treatment. Out of the nine patients, four recovered (44.4%) and five died (55.5%). <strong>Conclusion: </strong>COVID-19/TB coinfection had a low prevalence in our cohort, but was associated with a high mortality due to the frequent occurrence of severe forms of the disease.
%K COVID-19
%K Tuberculosis
%K Saint-Louis
%K Senegal
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=130725