%0 Journal Article
%T A Clinical Study to Assess the Effectiveness of Oral Combination Kit Therapy in Syndromic Management of Abnormal Vaginal Discharge (FEMINE Study) in Kinshasa, Democratic Republic of Congo
%A Feruzi Michel Mangala
%A Muela Andy Mbangama
%A Di-Mosi-Nkoy Roger Wumba
%A Ambis Jo£¿lle Lumaya
%A Nkongolo Freddy Muamba
%A Tshitadi Jean Mukendi
%A Ndombasi Neilda Lemba
%A Otem Christian Ndesanzim
%A Nkashama Bienvenu Kazadi
%A Banza Jesual Lotoy
%A Umba Adrien Tandu
%A Mushengezi Dieudonn¨¦ Sengeyi
%A Mwimba Roger Mbungu
%J Open Journal of Obstetrics and Gynecology
%P 193-208
%@ 2160-8806
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojog.2024.141018
%X Background: Vaginal discharge is one of most common and nagging problems that women
face. About 20% - 25% of women who visit
gynecology department complain of vaginal discharge and leucorrhoea. An orally
administered combination kit, containing 2 g
secnidazole, 1 g azithromycin
and 150 mg
fluconazole (Azimyn FS Kit), has been
successfully evaluated in clinical trials and used in several countries for
management syndromic vaginal discharge due to infections. Methods: This is a longitudinal
study which aimed to verify the clinical efficacy of the combined oral kit
containing secnidazole, azithromycin and fluconazole (Azimyn FS Kit®) in the
syndromic treatment of abnormal vaginal discharge in patients received in
outpatient consultations in Kinshasa/DR Congo from March to September 2023. Results: Majority of patients had
whitish vaginal discharge (51.6%) of average abundance (56.2%), accompanied by
pruritus in 72.1% of cases, and dyspareunia in 23.5% of cases and
hypogastralgia in 40.2% of cases. One week after treatment with the Azimyn FS® combined
kit, at the greatest majority of patients (97.3%), abnormal vaginal discharge
had decreased by more than 50% (84.1%). Two weeks after treatment with the
Azimyn FS