%0 Journal Article %T ¡°FISH VERTEBRA¡± about 3 Sickle Cell Patients Followed at Laquintinie Hospital, Douala %A Same Bebey Francine %A Mbono Betoko Ritha %A Eloundou Onomo Paul %A Mantho Fopa Pauline %A Eposse Ekoube Charlotte %A Megne Tamo Estelle %A Ebene Mbende Romain %A Singwe Ngandeu Madeleine %J Open Journal of Rheumatology and Autoimmune Diseases %P 20-25 %@ 2164-005X %D 2024 %I Scientific Research Publishing %R 10.4236/ojra.2024.141003 %X Vertebral involvement in particular is common in sickle cell patients. We report 3 cases of ¡°fish vertebra¡± fractures in sickle cell patients aged 16, 18, and 24 years old respectively at Laquintinie Hospital, Douala. When the vertebral fractures were diagnosed, the 3 patients had back pain and kyphosis deformities of the dorsal spine. Treatment with an infusion of biphosphonates (zoledronic acid at a dose of 0.5 mg¡€per¡€kg) was offered to all three patients. Two out of three patients received treatment with biphosphonates with a successful outcome. Profound vitamin D deficiency is associated with increased bone remodeling and a history of fractures. In sickle cell anemia, vertebral fractures may also result from bone fragility, which is often overlooked as aseptic osteonecrosis and osteomyelitis, which are very often suspected. %K Vertebral Fractures %K Sickle Cell Anemia %K Vertebral Bone Fragility %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131188