%0 Journal Article
%T ¡°FISH VERTEBRA¡± about 3 Sickle Cell Patients Followed at Laquintinie Hospital, Douala
%A Same Bebey Francine
%A Mbono Betoko Ritha
%A Eloundou Onomo Paul
%A Mantho Fopa Pauline
%A Eposse Ekoube Charlotte
%A Megne Tamo Estelle
%A Ebene Mbende Romain
%A Singwe Ngandeu Madeleine
%J Open Journal of Rheumatology and Autoimmune Diseases
%P 20-25
%@ 2164-005X
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojra.2024.141003
%X Vertebral involvement in particular is common in
sickle cell patients. We report 3 cases of ¡°fish vertebra¡± fractures in sickle cell patients
aged 16, 18, and 24 years old respectively at Laquintinie Hospital, Douala.
When the vertebral fractures were diagnosed, the 3 patients had back pain and
kyphosis deformities of the dorsal spine. Treatment with an infusion of
biphosphonates (zoledronic acid at a dose of 0.5 mg¡€per¡€kg) was offered to all three patients. Two
out of three patients received treatment with biphosphonates with a successful
outcome. Profound vitamin D deficiency is associated with increased bone
remodeling and a history of fractures. In sickle cell anemia, vertebral
fractures may also result from bone fragility, which is often overlooked as
aseptic osteonecrosis and osteomyelitis, which are very often suspected.
%K Vertebral Fractures
%K Sickle Cell Anemia
%K Vertebral Bone Fragility
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131188