%0 Journal Article
%T Small Cell Neuroendocrine Carcinoma of the Vulva: Case Report and Literature Review
%A Gabriela Fran£¿¨®es Rostirolla
%A Alessandra Guerra
%A Maria Carolina Rey Alt
%A Luiza Tesser Dalla Libera
%A Maria Eduarda Appel Binda
%A M¨¢rcia Appel
%A Fernando De Marco dos Santos
%J Open Journal of Obstetrics and Gynecology
%P 295-300
%@ 2160-8806
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojog.2024.142027
%X <strong>Background</strong><strong>: </strong><span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">Neuroendocrine neoplasms are those that develop from
a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal
tract, and pancreas, being rare conditions in the female genital tract. When
present, these neoplasms often manifest with nonspecific signs and symptoms
such as pain, itching, swelling, single-focus lesions, bleeding, and
enlargement of inguinal lymph nodes, in addition to the presence of
progressively enlarging vulvar nodules. Consequently, the diagnostic
investigation involves histopathological examination and confirmation through
immunohistochemistry. </span><b><span style=\"font-family:Verdana;\">Objective: </span></b><span style=\"font-family:Verdana;\">To present a comprehensive
understanding of this rarely studied pathology. The primary objective is to
provide valuable insights that could aid in the future development of
universally applicable treatment guidelines. </span><b><span style=\"font-family:Verdana;\">Case Presentation:</span></b><span style=\"font-family:Verdana;\"> A
57-year-old female, with no prior comorbidities, menopause at 36, who presented
with a left vulvar nodule accompanied by intense pain and swelling, later
diagnosed with small cell neuroendocrine carcinoma in the vulva. </span><b><span style=\"font-family:Verdana;\">Conclusion: </span></b><span style=\"font-family:Verdana;\">This case report highlights the importance of enhancing our knowledge
regarding small cell neuroendocrine carcinoma in the vulva, given its scarcity
in medical literature. The information presented here underscores the need for
standardized diagnostic and treatment approaches, paving the way for future
consensus on managing this uncommon but challenging neoplasm.</span></span></span>
%K Vulvar Neoplasms
%K Carcinoma
%K Small Cell
%K Carcinoma
%K Neuroendocrine
%K Genital Neoplasms
%K Female
%K Vulvar Diseases
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131439