%0 Journal Article
%T Perinatal Morbidity, Mortality, and Neurodevelopmental Outcomes of Neonates with Fetal Growth Restriction
%A Natsuki Tamashiro
%A Shuko Chinen
%A Yoshino Kinjyo
%A Yukiko Chinen
%A Tadatsugu Kinjo
%A Keiko Mekaru
%J Open Journal of Obstetrics and Gynecology
%P 321-333
%@ 2160-8806
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojog.2024.143030
%X <strong>Objective:</strong> <span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">This study aimed to assess perinatal morbidity, mortality rates, and
neurodevelopmental outcomes in the management of fetal growth restriction (FGR)
at a single tertiary institute. </span><b><span style=\"font-family:Verdana;\">Methods:</span></b><span style=\"font-family:Verdana;\"> Among 2465 deliveries between
2013 and 2019, 109 cases of FGR were reviewed retrospectively for causes,
indications for pregnancy termination, perinatal death, overall neonatal
outcomes, and long-term prognosis. </span><b><span style=\"font-family:Verdana;\">Results:</span></b><span style=\"font-family:Verdana;\"> Excluding FGR due to
congenital anomalies (n = 17), the mortality rate was 3.3% (3/92). One neonate
delivered at 23 weeks developed cerebral palsy (1.1%). Retinopathy of
prematurity occurred in four neonates (4.3%). Neurodevelopmental disorders were
present in six neonates (6.5%), all of whom were delivered at 32</span></span><span style=\"font-family:Verdana;\"> - </span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">38 weeks. Significantly
lower gestational age at delivery, lower birth weight, and higher umbilical
artery resistance indices were observed in neonates with neurodevelopmental
disorders. </span><b><span style=\"font-family:Verdana;\">Conclusions:</span></b></span><b><span style=\"font-family:;\" \"=\"\"> </span></b><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">Intact survival before 27 weeks of gestation at delivery with FGR is
uncommon</span></span><span style=\"font-family:;\" \"=\"\"><span style=\"font-family:Verdana;\">. </span><span style=\"font-family:Verdana;\">Neurodevelopmental
disorders may still develop after delivery at 32</span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> - </span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\">38 weeks</span></span><span style=\"font-family:Verdana;\">;
consideration should be given to the timing of delivery usingfetal ductus
venosus Doppler waveforms measurements to reduce neurodevelopmental disorders.</span>
%K Fetal Death
%K Fetal Growth Retardation
%K Neurodevelopmental Disorders
%K Perinatal Mortality
%K Umbilical Artery Doppler Velocimetry
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=131649