%0 Journal Article
%T 香豆素类化合物合成研究进展<br>Research Progress in synthesis of Coumarins
%A 谭玉杰
%J Journal of Organic Chemistry Research
%P 17-30
%@ 2330-524X
%D 2024
%I Hans Publishing
%R 10.12677/JOCR.2024.121002
%X 香豆素是一种以特定的苯并吡喃酮为母核的化合物。自1820年香豆素自唐卡豆中分离出来后，不同的香豆素及其衍生物被研究证实为具有抗凝血、抗肿瘤、抗病毒、抗炎、抗氧化、抗微生物和酶抑制等作用。本文综述了香豆素母核结构的几种经典合成方法，总结了香豆素及其衍生物的合成研究进展，并对香豆素未来的发展进行了展望。<br />
Coumarin is a compound with a specific benzopyrone as its parent nucleus. Since the isolation of coumarin from Tonka bean in 1820, different coumarins and their derivatives have been investigated and confirmed to possess anticoagulant, antitumor, antiviral, anti-inflammatory, antioxidant, anti-microbial, and enzyme inhibitory effects. In this review, we summarize several classical synthesis methods of the nuclear structure, summarize the synthesis of coumarins and its derivatives, and discuss the future development of coumarins.
%K 香豆素，抗肿瘤，合成方法<br>Coumarin
%K Antitumor
%K Synthetic Methods
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=83173