%0 Journal Article
%T 可见光光氧化还原催化C-F键断裂的研究进展<br>Recent Advances in C-F Bond Cleavage Enabled by Visible Light Photoredox Catalysis
%A 张菲杰
%J Journal of Organic Chemistry Research
%P 136-147
%@ 2330-524X
%D 2024
%I Hans Publishing
%R 10.12677/jocr.2024.121011
%X 通过容易获得的单氟或低氟化合物的C-F键裂解来产生新键受到越来越多的科学家的关注。通过这种方法，可以制备出很多有价值的氟化产品，传统的C-F键形成方法很难制造这些产品。可见光光氧化还原催化由于其温和、易于处理和环境友好的特性，已被证明是脱氟反应的重要而强大的工具。与通过双电子过程进行的经典C-F活化相比，自由基是使用可见光光氧化还原催化的关键中间体，为C-F键的断裂提供了新的方式。在这篇综述中，总结了自2018年以来可见光促进的C-F键断裂的偕-二氟烯烃、三氟甲基芳烃和三氟甲基烯烃。<br />
The generation of new bonds by C-F bond cleavage of readily available monofluorinated or low-fluorinated compounds has received increasing attention from scientists. By this method, many valuable fluorinated products can be prepared, which are difficult to make with traditional C-F bond formation methods. Visible light photoredox catalysis has proven to be an important and powerful tool for defluorination reactions due to its mild, easy to handle and environmentally friendly properties. In contrast to classical C-F activation via a two-electron process, free radicals are key intermediates catalyzed by photoredox using visible light, providing a new mode for C-F bond breaking. In this review, GEM-difluoroolefins, trifluoromethylarenes, and trifluoromethylolefins with visible-facilitated C-F bond breakage since 2018 are summarized.
%K 可见光，自由基，C-F键裂解，光氧化还原<br>Visible Light
%K Radical
%K C-F Bond
%K Cleavage
%K Photoredox
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=83621