%0 Journal Article
%T 铜绿假单胞菌肺部感染动物模型<br>Animal Models of <i>Pseudomonas </i><i>aeruginosa</i> Lung Infection
%A 詹华婵
%A 支芸琪
%A 龙运鸿
%J Hans Journal of Biomedicine
%P 145-156
%@ 2161-8984
%D 2024
%I Hans Publishing
%R 10.12677/hjbm.2024.142016
%X 铜绿假单胞菌是一种具有很强抗生素耐药性的条件致病菌，能够引起广泛的危及生命的急性和慢性感染。它是细菌性肺部感染的主要病原菌之一，具有很高的发病率和死亡率。建立有效、合适的动物模型能够极大地帮助我们了解疾病的发病机制以及测试和开发新的治疗策略。本文旨在通过对以铜绿假单胞菌为病原菌建立的动物肺炎模型方法的概述及评价，为基础与临床研究应用提供理论基础。<br />
<i>Pseudomonas aeruginosa</i> is a highly antibiotic-resistant conditionally pathogenic bacterium capable of causing a wide range of life-threatening acute and chronic infections. It is one of the major pathogens of bacterial lung infections with high morbidity and mortality. The establishment of effective and appropriate animal models can greatly assist our understanding of disease pathogenesis as well as testing and developing new therapeutic strategies. The aim of this paper is to provide a theoretical basis for basic and clinical research applications by detailing and evaluating the methodology of animal pneumonia models established using <i>Pseudomonas aeruginosa</i> as the causative agent.
%K 铜绿假单胞菌，急性感染，慢性感染，动物模型<br><i>Pseudomonas </i><i>aeruginosa</i>
%K Acute Infection
%K Chronic Infection
%K Animal Model
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=84561