%0 Journal Article
%T Synthesis of 4-[F-18]Fluoro-4-Deoxy-<i>N</i>-Acetyl-1,3,6-Tri-<i>O</i>-Acetylglucosamine, a Potential Brain Imaging PET Agent
%A Murthy Akula
%A Derek Cressy
%A Lee Collier
%A George Kabalka
%A Dustin Osborne
%J Natural Science
%P 19-23
%@ 2150-4105
%D 2024
%I Scientific Research Publishing
%R 10.4236/ns.2024.163003
%X The synthesis of a promising brain imaging agent 4-[F-18]fluoro-4-deoxy-N-acetyl-1,3,6-tri-O-acetylglucosamine, 2, was successfully accomplished from commercially available N-acetyl glucosamine in 5 steps. The non-decay corrected radiochemical yield and purity were found to be 31% ± 4% (n = 3) and >98% respectively. The total reaction time for radio labelling step was 50 min.
%K N-Acetylglucosamine
%K Amyloidogenesis
%K Lipase-&lt
%K i&gt
%K Candida &lt
%K /i&gt
%K &lt
%K i&gt
%K r&lt
%K /i&gt
%K &lt
%K i&gt
%K ugosa&lt
%K /i&gt
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=132470