%0 Journal Article
%T Quantitative Assessment of Liver Fibrosis by Elastography in Patients with Chronic Liver Disease: A Cross-Sectional Study in Lomé (Togo)
%A Massaga Dagbe
%A Bidamin N&#8217
%A timon
%A Sonia Ekembe
%A Rafiou El-Hadji Yakoubou
%A Pihou Gbande
%A Lantam Sonhaye
%A Lama Kegdigoma Agoda-Koussema
%A Komlanvi Victor Adjenou
%J Open Journal of Radiology
%P 42-54
%@ 2164-3032
%D 2024
%I Scientific Research Publishing
%R 10.4236/ojrad.2024.142005
%X <b>Aim:</b> To describe the two-dimensional elastographic profile according to the Shearwave (2D-SWE) technique in patients with chronic liver disease in Lomé. <b>Materials and method:</b> Cross-sectional, descriptive study conducted over seven month at the Autel d’Elie Clinic in Lomé, from January to August 2022, on adult patients with chronic liver disease who underwent abdominal ultrasound coupled with two-dimensional elastography. <b>Results: </b>The sample size was 54 patients. The mean age of the patients was 33 ± 12 years, with extremes of 18 and 66 years. Patients aged 30 years or less accounted for 48.1% (n = 26). All patients (n = 54) had at least one transaminase assay with a mean of 69.3 ± 78.3 IU/l (AST) and 59.3 ± 82.8 IU/l (ALT). There was no statistically significant association between the biological parameters and the presence of fibrosis. Viral liver disease was the main cause, accounting for 81.5% (n = 44) of cases, with no significant association with the degree of fibrosis. Ultrasound revealed a dysmorphic liver (57.4%; n = 31) and portal hypertension (18.5%, n = 10). Fibrosis stages F1, F2 and F4 accounted for (48.1%, n = 26), (24.1%, n = 13) and (13%, n = 7) of cases respectively. Liver dysmorphia was significantly associated with the presence of fibrosis (p = 0.012) and portal hypertension was significantly associated with the degree of fibrosis (p = 0.0063). <b>Conclusion: </b>Assessment of liver fibrosis in patients with chronic liver disease using 2D-SWE elastography is essential for patient follow-up.
%K Hepatic Fibrosis
%K 2D-SWE Elastography
%K Chronic Liver Disease
%K Lom&amp
%K #233
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=133194