%0 Journal Article
%T 沏其日甘-8丸治疗血栓闭塞性脉管炎主药、辅药、佐药化学成分及药理作用研究进展<br>Research Progress on the Chemical Constituents and Pharmacological Effects of the Main, Auxiliary and Adjuvant Drugs in the Treatment of Thromboangiitis Obliterans by Mongolian Medicine Qiqirigan-8
%A 马明星
%A 孟根杜希
%A 安娜
%J Pharmacy Information
%P 289-297
%@ 2160-4452
%D 2024
%I Hans Publishing
%R 10.12677/pi.2024.133034
%X 血栓闭塞性脉管炎又称脉管炎，多发于中青年男性，近年来女性患者也逐渐增加。它的病因与长期吸烟、感染、牙周炎与激素紊乱等多种状态息息相关。脉管炎多发在四肢的中小动脉或静脉，并且伴有继发的神经性、缺血性改变，下肢多见。临床表现为早期的患肢发冷、间歇性跛行，严重后则可演变为患肢静息痛、坏疽等。且在临床中难以治愈，因此，有效治疗血栓闭塞性脉管炎，提高患者生活质量是亟待解决的问题之一。在改善血栓闭塞性脉管炎患者症状、减轻痛苦方面，蒙医药有着独特的见解及处方。沏其日甘-8丸在临床中用于心脑血管疾病，具有较好的临床效果，具有抗炎、抗血小板聚集、抗氧化、改善血流变学、抑制血栓、清理血管以及控制血脂水平的效果。鉴于此，本文对沏其日甘-8丸治疗血栓闭塞性脉管炎的相关主药、辅药、佐药的活性化学成分、药理作用进行梳理，为临床以及科研等提供参考。<br />
Thromboangiitis obliterans, also known as vasculitis, is more common in middle-aged and young men, and in recent years, the number of female patients has gradually increased. Its etiology is closely related to various conditions such as long-term smoking, infection, periodontitis, and hormonal imbalances. Vasculitis often occurs in the small and medium-sized arteries or veins of the limbs, accompanied by secondary neurological and ischemic changes, and is more common in the lower limbs. The clinical manifestations include early chills and intermittent claudication in the affected limb, and in severe cases, it can evolve into resting pain and gangrene in the affected limb. And it is difficult to cure in clinical practice, therefore, effectively treating TAO and improving the quality of life of patients is one of the urgent problems to be solved. Mongolian medicine has unique insights and prescriptions in improving symptoms and alleviating pain in patients with TAO. Qiqirigan-8 is used in clinical practice for cardiovascular and cerebrovascular diseases, and has good clinical effects. It has anti-inflammatory, antiplatelet aggregation, antioxidant, improving hemorheology, inhibiting thrombosis, clearing blood vessels, and controlling blood lipid levels. In view of this, this article reviews the active chemical components and pharmacological effects of the main drugs, auxiliary drugs, and adjuvants used in the treatment of TAO with Qiqirigan-8, providing reference for clinical and scientific research.
%K 沏其日甘-8丸，血栓闭塞性脉管炎，活性成分，药理作用<br>Qiqirigan-8
%K Thromboangiitis Obliterans
%K Active Ingredients
%K Pharmacological Action
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=87913