%0 Journal Article
%T 高胰岛素血症及胰岛素抵抗的研究进展<br>Research Progress on Hyperinsulinemia and Insulin Resistance
%A 黎玉婷
%A 林显光
%A 李臣鸿
%J Hans Journal of Biomedicine
%P 353-358
%@ 2161-8984
%D 2024
%I Hans Publishing
%R 10.12677/hjbm.2024.143039
%X 高胰岛素血症及胰岛素抵抗是2型糖尿病和肥胖的主要代谢特征，可由遗传和生活方式等因素导致。二者在部分癌症的发生发展过程中可能起重要促进作用。本文就高胰岛素血症和胰岛素抵抗的关系，和所涉及的部分通路以及两者对其它癌症的影响进行综述，为研发新型缓解药物提供依据。<br />
Hyperinsulinemia and insulin resistance are the main metabolic features of type 2 diabetes and obesity, which can be caused by genetic and lifestyle factors. The two may play an important role in the occurrence and development of some cancers. This article reviews the relationship between hyperinsulinemia and insulin resistance, some of the pathways involved, and the effects of the two on other cancers, so as to provide a basis for the development of new remission-seeking drugs.
%K 高胰岛素血症，胰岛素抵抗，NOS，cAMP-PKA，PI3K-PKB(Akt)<br>Hyperinsulinemia
%K Insulin Resistance
%K NOS
%K cAMP-PKA
%K PI3K-PKB (Akt)
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=88940