%0 Journal Article
%T Delay Times and Clinical Outcomes in Acute Myocardial Infarction: Comparison of Periods before and during the COVID-19 Pandemic<br>&#8212;Myocardial Infarction and the Pandemic
%A Clarice Teixeira Silva Ara&#250
%A jo
%A Arnon Salviato Mameri
%A Th¨²lio Carrera Guar£¿oni Venturini
%A Marcus Tadeu Aguilar Constantino Matos
%A Igor Morais Araujo Lopes
%A Luiz Gustavo Ribeiro de Carvalho Murad
%A Cleberson Duartes Ovani
%A Guilherme Vassalo Morais
%A Fernanda Venturini de Castro
%A Danielle Lopes Rocha
%A Lucas Crespo de Barros
%A Rodolfo Costa Sylvestre
%A Luiz Fernando Machado Barbosa
%A Roberto Ramos Barbosa
%J World Journal of Cardiovascular Diseases
%P 392-400
%@ 2164-5337
%D 2024
%I Scientific Research Publishing
%R 10.4236/wjcd.2024.146033
%X <b>Introduction: </b>At the beginning of the COVID-19 pandemic, a drop in the number of patients treated for cardiac emergencies raised concern about cardiovascular mortality in that period. An increase in care delay for patients with ST-segment elevation myocardial infarction (STEMI) may have affected clinical outcomes. <b>Objectives: </b>To analyze delay times and clinical outcomes of patients with STEMI undergoing primary percutaneous coronary intervention (PPCI), before and during the COVID-19 pandemic. <b>Methods: </b>Retrospective observational study that included patients with STEMI undergoing PPCI from December 2018 to July 2021. The COVID-19 pandemic cases were divided into two groups: pandemic I&#8212;from March to August 2020; and pandemic II&#8212;from September 2020 to July 2021. Patients were compared according to the period of hospitalization. Primary outcomes were delay times in assistance and clinical outcomes (acute kidney injury [AKI], post-procedural vascular complications and in-hospital mortality).<b> Results: </b>108 patients were included, 39 (36.1%) in the pre-pandemic period, 13 (12.1%) in pandemic I and 56 (51.8%) in pandemic II. Time from onset of symptoms to arrival at the service and door-to-balloon time did not differ significantly among groups. Vascular complications were more frequent during the pandemic (I and II) than in the pre-pandemic period (2.5% pre-pandemic vs 15.4% pandemic vs 12.5% pandemic II; p = 0.03). AKI incidence was similar in all three periods. There was a non-significant increase in in-hospital mortality during the COVID-19 pandemic.<b> Conclusion: </b>In patients with STEMI, there was an increase in vascular complications and a trend toward increased mortality during the COVID-19 pandemic. Delay times to admission and reperfusion did not differ significantly between before and during the pandemic.
%K Myocardial Infarction
%K Primary Percutaneous Coronary Intervention
%K Coronary Reperfusion
%K Pandemic
%K COVID-19
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=134144