%0 Journal Article
%T Fournier’s Gangrene: A Review of Fournier’s Gangrene Severity Index (FGSI) and Other Predictors of Mortality
%A Makama Baje Salihu
%A Haruna Liman
%A Stephen Yusuf
%A Aminu Umar
%A Abraham Tunde Oladimeji
%A Aremu Abdulrazak
%J Open Journal of Urology
%P 391-399
%@ 2160-5629
%D 2024
%I Scientific Research Publishing
%R 10.4236/oju.2024.147041
%X <b>Background</b><b>:</b> Fournier gangrene is an acute and rapidly progressive necrotizing fasciitis of the scrotum, perianal and perineal region of the body. It is a polymicrobial infection having an interplay of both anaerobic and aerobic orgasms in a soup of microbial disaster. Fournier&#8217;s gangrene was also initially thought to be an idiopathic condition but a lot of risk factors have been associated now with this condition, both systemic risk factors and local. Systemic risk factors include diabetes mellitus, HIV/AIDS, cancers, chronic liver disease, chronic steroid use etc. The local risk factors include perineal injuries, watering can perineum, perianal abscess, chronic perineal itching etc. <b>Pu</b><b>r</b><b>pose</b><b>:</b> The swiftly flourishing bacteria orgasms cause a similar disruptive event in the body of the patients both clinically and biochemically and these can be used to create a predictive score or index for patients in order to assess the disease severity and guide in the management and prognostication of this condition. <b>Materials</b> <b>and</b> <b>Method</b><b>:</b> Urology ward record books, clinic record books and operating theater records were used to identify patients managed for Fournier gangrene in ATBUTH Bauchi. A retrospective study of the medical files of all the patients managed from January 2011 to January 2024 was done. Folders were retrieved and the medical records were reviewed. <b>Results</b><b>:</b> Of the 50 patients reviewed, Male to female ratio is 24:1. The mean age is 56 years (2 weeks to 97 years). Mortality rate was 34%. There is a significant difference between delayed presentation/initial use of unorthodox treatment with mortality (p = 0.002). Of the 17 patients that died, 15 had FGSI &gt; 9 and of the 33 patients that survived 29 had FGSI &lt; 9, thus the mortality rate for those with FGSI &gt; 9 is 88.2% while the mortality rate for those with FGSI &lt; 9 is 12.1%, and the statistical difference was significant (p = 0.001). All the mortalities had more than one microorganism isolated (polymicrobial). The mortality rate for polymicrobial is 48% while that for monomicrobial is 0%. The difference was significant (p = 0.001). <b>Conclusion</b><b>:</b> knowledge of the predictors of its mortality is necessary in other to help stratify patients and ensure the best response by the caregivers. FGSI, delayed presentation/initial patronage of unorthodox care, and polymicrobial infection are important predictors of mortality in this condition.
%K Fournier&#8217
%K s
%K Gangrene
%K FGSI
%K Risk Factors
%K Mortality
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=134448